Exposure to the BPA-Substitute Bisphenol S Causes Unique Alterations of Germline Function

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Exposure to the BPA-Substitute Bisphenol S Causes Unique Alterations of Germline Function

Concerns about the safety of Bisphenol A, a chemical found in plastics, receipts, food packaging and more, have led to its replacement with substitutes now found in a multitude of consumer products. However, several popular BPA-free alternatives, such as Bisphenol S, share a high degree of structural similarity with BPA, suggesting that these substitutes may disrupt similar developmental and re...

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1 Human Exposure to Bisphenol a ( Bpa )

Acknowedgements: The authors gratefully acknowledge expertise and input from additional panel members: Jane C. Atkinson, Antonia M. Calafat, Frederick Eichmiller, Albert Kingman, Ruthann Rudel, and Kristina A. Thayer. This review was prepared in conjunction with the Bisphenol A Conference, Chapel Hill, NC, November 28-29, 2006. Support was provided by the National Institute of Environmental Hea...

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Health risk of exposure to Bisphenol A (BPA).

Bisphenol A (BPA) belongs to chemicals that are produced in large quantities worldwide. It is commonly used as monomer in polycarbonate synthesis, plasticizer in the production of epoxy resins, as well as an additive for the elimination of surfeit of hydrochloric acid during the polyvinyl chloride (PVC) production. BPA is not only used in the production of plastics intended to a direct contact ...

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Occupational exposure to bisphenol-A (BPA) and the risk of self-reported male sexual dysfunction.

BACKGROUND Animal studies have suggested that bisphenol-A (BPA) is a potential human endocrine disrupter; but evidence from human studies is needed. METHODS We conducted an occupational cohort study to examine the effect of occupational exposure to BPA on the risk of male sexual dysfunction. Current workers from BPA-exposed and control factories were recruited. The exposed workers were expose...

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The BPA-substitute bisphenol S alters the transcription of genes related to endocrine, stress response and biotransformation pathways in the aquatic midge Chironomus riparius (Diptera, Chironomidae)

Bisphenol S (BPS) is an industrial alternative to the endocrine disruptor bisphenol A (BPA), and can be found in many products labeled "BPA-free". Its use has grown in recent years, and presently it is considered a ubiquitous emerging pollutant. To date there is a lack of information on the effects of BPS on invertebrates, although they represent more than 95% of known species in the animal kin...

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ژورنال

عنوان ژورنال: PLOS Genetics

سال: 2016

ISSN: 1553-7404

DOI: 10.1371/journal.pgen.1006223